A New Electrochemical Sensor for Determination of Zolpidem by Carbon Paste Electrode Modified with SnS@SnO2NP

Zolpidem is a drug that is easily attached to the GABA receptors in the brain. This property makes it very effective for tranquilizing as well as hypnagogia. According to the advantages of electrochemical analysis like high selectivity, high sensitivity, low concentration of analyte, cost-effective, portable and easy-to-use setup, they gained high amount of attention among scientists for determination of different compounds. So in the work, an electrochemical sensor was prepared by the modification of a carbon paste with sulfur-tin@tin oxide nanocomposite (SnS@SnO2NP/CPE) and was investigated for the determination of zolpidem in an aqueous solution. For this reason the electrochemical characteristic of SnS@SnO2NP /CPE including cyclic voltammetry and electrochemical impedance techniques were used. Cyclic voltammetry studies indicated that the process was irreversible. Determination of zolpidem was performed using differential pulse differential technique at the modified electrode surface and linear relationship of oxidation peak current with concentration of this drug show a LOD of 0.66 μM was in the range of 2-80 μM.